BDBM50037901 CHEMBL3358253

SMILES: CN(C)CCNC(=O)C(Cc1ccc(cc1)-c1cc(nn1C)C(F)(F)F)NC(=O)c1ccccc1OCc1ccccc1

InChI Key: InChIKey=LEAFRVMELBUZIA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50037901   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein KIFC1 (Homo sapiens (Human))	BDBM50037901 (CHEMBL3358253) Show SMILES CN(C)CCNC(=O)C(Cc1ccc(cc1)-c1cc(nn1C)C(F)(F)F)NC(=O)c1ccccc1OCc1ccccc1 Show InChI InChI=1S/C32H34F3N5O3/c1-39(2)18-17-36-31(42)26(19-22-13-15-24(16-14-22)27-20-29(32(33,34)35)38-40(27)3)37-30(41)25-11-7-8-12-28(25)43-21-23-9-5-4-6-10-23/h4-16,20,26H,17-19,21H2,1-3H3,(H,36,42)(H,37,41)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal His6-tagged KIFC1 (Q305-K673 aa) (unknown origin) expressed in Escherichia coli BL21 (DE3) by malachite green as...				J Med Chem 57: 9958-70 (2014) Article DOI: 10.1021/jm501179r BindingDB Entry DOI: 10.7270/Q2QF8VG8
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