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BDBM50037954 CHEMBL3358283

SMILES: C\C=C\c1cc(ccc1C)C(=O)N[C@@H](Cc1ccc(cc1)-c1cccc(c1)C(F)(F)F)C(O)=O

InChI Key: InChIKey=XLTMFKMBNAYIMC-QCLFJWPPNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50037954   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein KIFC1


(Homo sapiens (Human))
BDBM50037954
PNG
(CHEMBL3358283)
Show SMILES C\C=C\c1cc(ccc1C)C(=O)N[C@@H](Cc1ccc(cc1)-c1cccc(c1)C(F)(F)F)C(O)=O |r|
Show InChI InChI=1/C27H24F3NO3/c1-3-5-20-15-22(11-8-17(20)2)25(32)31-24(26(33)34)14-18-9-12-19(13-10-18)21-6-4-7-23(16-21)27(28,29)30/h3-13,15-16,24H,14H2,1-2H3,(H,31,32)(H,33,34)/b5-3+/t24-/s2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.02E+4n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal His6-tagged KIFC1 (Q305-K673 aa) (unknown origin) expressed in Escherichia coli BL21 (DE3) by malachite green as...


J Med Chem 57: 9958-70 (2014)


Article DOI: 10.1021/jm501179r
BindingDB Entry DOI: 10.7270/Q2QF8VG8
More data for this
Ligand-Target Pair