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BDBM50038002 Benzamidine (Protonated)::CHEMBL20936::CHEMBL537204::benzamidine
SMILES: NC(=N)c1ccccc1
InChI Key: InChIKey=PXXJHWLDUBFPOL-UHFFFAOYSA-N
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Trypsin (Bos taurus (bovine)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet  | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory Activity against bovine trypsin | J Med Chem 43: 3033-44 (2000) BindingDB Entry DOI: 10.7270/Q20R9Q3N | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Trypsin (Bos taurus (bovine)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description In vitro binding affinity by measuring the inhibition of bovine trypsin | J Med Chem 37: 3889-901 (1994) BindingDB Entry DOI: 10.7270/Q25X29KK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor X (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design Curated by ChEMBL | Assay Description Inhibitory concentration against human Coagulation factor Xa (fXa) | J Med Chem 45: 1221-32 (2002) BindingDB Entry DOI: 10.7270/Q2319V5W | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prothrombin (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description In vitro binding affinity by measuring the inhibition of human thrombin | J Med Chem 37: 3889-901 (1994) BindingDB Entry DOI: 10.7270/Q25X29KK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prothrombin (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory Activity against human thrombin | J Med Chem 43: 3033-44 (2000) BindingDB Entry DOI: 10.7270/Q20R9Q3N | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor X (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | 410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences Curated by ChEMBL | Assay Description Binding affinity of the compound was evaluated against Coagulation factor X | Bioorg Med Chem Lett 8: 1877-82 (1999) BindingDB Entry DOI: 10.7270/Q2222SX9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prothrombin (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | 1.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Parma Curated by ChEMBL | Assay Description Binding affinity against human thrombin | J Med Chem 45: 2469-83 (2002) BindingDB Entry DOI: 10.7270/Q28916J7 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prothrombin (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | 1.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Parma Curated by ChEMBL | Assay Description Binding affinity against human thrombin | J Med Chem 45: 2469-83 (2002) BindingDB Entry DOI: 10.7270/Q28916J7 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Acrosin (Sus scrofa) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Reversible competitive inhibition of boar spermatozoa acrosin using BzArgOEt as substrate by Dixon plot analysis | J Med Chem 21: 1132-6 (1979) BindingDB Entry DOI: 10.7270/Q2TT4SGN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Plasminogen (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | 7.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Competitive inhibition of esterase activity of human plasmin assessed as assessed as decrease in p-nitrophenol production using N-Z-L-Tyr-ONp as subs... | J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glutamate delta 2 (Xenopus) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Curated by PDSP Ki Database | J Pharmacol Exp Ther 305: 740-8 (2003) Article DOI: 10.1124/jpet.102.045799 BindingDB Entry DOI: 10.7270/Q2N878C5 | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Trypsin-1 (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | 1.84E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Parma Curated by ChEMBL | Assay Description Binding affinity against bovine trypsin | J Med Chem 45: 2469-83 (2002) BindingDB Entry DOI: 10.7270/Q28916J7 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Trypsin-1 (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | 1.84E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Parma Curated by ChEMBL | Assay Description Binding affinity against bovine trypsin | J Med Chem 45: 2469-83 (2002) BindingDB Entry DOI: 10.7270/Q28916J7 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Trypsin (Bos taurus (bovine)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design Curated by ChEMBL | Assay Description Inhibitory concentration against bovine trypsin | J Med Chem 45: 1221-32 (2002) BindingDB Entry DOI: 10.7270/Q2319V5W | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Trypsin (Bos taurus (bovine)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | Article | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
TBA Curated by ChEMBL | Assay Description Tested for the Inhibition of the catalytic activity of bovine trypsin at 25 degree C and pH 7.5. | Bioorg Med Chem Lett 7: 1283-1288 (1997) Article DOI: 10.1016/S0960-894X(97)00210-2 BindingDB Entry DOI: 10.7270/Q29W0FZ9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Trypsin (Bos taurus (bovine)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 3.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut für Biochemie Curated by ChEMBL | Assay Description Inhibitory activity against bovine trypsin expressed as dissociation constant | J Med Chem 41: 5445-56 (1999) Article DOI: 10.1021/jm981068g BindingDB Entry DOI: 10.7270/Q2KK99ZF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor X (Bos taurus) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 1.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut für Biochemie Curated by ChEMBL | Assay Description Inhibitory activity against bovine coagulation factor X expressed as dissociation constant | J Med Chem 41: 5445-56 (1999) Article DOI: 10.1021/jm981068g BindingDB Entry DOI: 10.7270/Q2KK99ZF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Urokinase-type plasminogen activator (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 1.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut für Biochemie Curated by ChEMBL | Assay Description Inhibitory activity against human urokinase plasminogen activator expressed as dissociation constant | J Med Chem 41: 5445-56 (1999) Article DOI: 10.1021/jm981068g BindingDB Entry DOI: 10.7270/Q2KK99ZF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prothrombin (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | Article | 2.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
TBA Curated by ChEMBL | Assay Description Tested for the Inhibition of the catalytic activity of human Thrombin at 25 degree C and pH 7.5. | Bioorg Med Chem Lett 7: 1283-1288 (1997) Article DOI: 10.1016/S0960-894X(97)00210-2 BindingDB Entry DOI: 10.7270/Q29W0FZ9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor III/Factor VIIa (fVIIa) (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 2.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. Curated by ChEMBL | Assay Description Inhibition of human soluble tissue factor/factor VIIa expressed in Origami B (DE3) using D-Ile-Pro-Arg-pNA as substrate after 30 mins by spectrophoto... | J Med Chem 58: 2799-808 (2015) Article DOI: 10.1021/jm501982k BindingDB Entry DOI: 10.7270/Q28D007C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prothrombin (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | 2.58E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps-University Marburg Curated by ChEMBL | Assay Description Binding affinity to thrombin (unknown origin) | J Med Chem 58: 6960-71 (2015) BindingDB Entry DOI: 10.7270/Q26M38M6 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Plasminogen (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | Article | 3.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
TBA Curated by ChEMBL | Assay Description Tested for the Inhibition of the catalytic activity of human plasmin at 25 degree C and pH 7.5. | Bioorg Med Chem Lett 7: 1283-1288 (1997) Article DOI: 10.1016/S0960-894X(97)00210-2 BindingDB Entry DOI: 10.7270/Q29W0FZ9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Matriptase (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 4.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Aurigene Discovery Technologies Limited Curated by ChEMBL | Assay Description Inhibition of matriptase-SP1 (615 to 855) (unknown origin) expressed in Escherichia coli BL21(DE3) using Boc-Gln-Ala-Arg-7-amido-4-methyl coumarin hy... | ACS Med Chem Lett 4: 1152-7 (2013) Article DOI: 10.1021/ml400213v BindingDB Entry DOI: 10.7270/Q29S1SHZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Plasminogen (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | 5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Competitive inhibition of esterase activity of human plasmin assessed as assessed as decrease in p-nitrophenol production using N-Z-L-Tyr-ONp as subs... | J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Complement C1s (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | 6.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Competitive inhibition of esterase activity of human plasmin assessed as assessed as decrease in p-nitrophenol production using N-Z-L-Tyr-ONp as subs... | J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thrombin (Bos taurus (Bovine)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 8.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut für Biochemie Curated by ChEMBL | Assay Description Inhibitory activity against bovine thrombin expressed as dissociation constant | J Med Chem 41: 5445-56 (1999) Article DOI: 10.1021/jm981068g BindingDB Entry DOI: 10.7270/Q2KK99ZF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tissue-type plasminogen activator (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 9.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut für Biochemie Curated by ChEMBL | Assay Description Inhibitory activity against human tissue-type plasminogen activator expressed as dissociation constant | J Med Chem 41: 5445-56 (1999) Article DOI: 10.1021/jm981068g BindingDB Entry DOI: 10.7270/Q2KK99ZF | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (docked) | ||||||||||||
| Prothrombin (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | 1.30E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Competitive inhibition of esterase activity of human plasmin assessed as assessed as decrease in p-nitrophenol production using N-Z-L-Tyr-ONp as subs... | J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thrombin & trypsin (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.82E+4 | n/a | n/a | n/a | n/a | n/a |
Harvard University Curated by ChEMBL | Assay Description Binding affinity against trypsin | J Med Chem 45: 2770-80 (2002) Article DOI: 10.1021/jm0105833 BindingDB Entry DOI: 10.7270/Q2MG7S8S | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Trypsin II (Bos taurus) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.48E+7 | n/a | n/a | n/a | n/a | n/a |
Harvard University Curated by ChEMBL | Assay Description log Kd (Binding affinity against specified protein) value of the compound | J Med Chem 45: 2770-80 (2002) Article DOI: 10.1021/jm0105833 BindingDB Entry DOI: 10.7270/Q2MG7S8S | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prothrombin (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 4.55E+5 | n/a | n/a | n/a | n/a | n/a |
Philipps-University Marburg Curated by ChEMBL | Assay Description Binding affinity to thrombin (unknown origin) by displacement titration based isothermal titration colorimetry | J Med Chem 58: 6960-71 (2015) BindingDB Entry DOI: 10.7270/Q26M38M6 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Kallikrein 5 (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.01E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human recombinant 6His-Q-FLAG-tagged KLK5 expressed in baculovirus infected Sf9 insect cells using rhodamine-labelled tripeptide as sub... | Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126675 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prothrombin (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 3.55E+5 | n/a | n/a | n/a | n/a | n/a |
Philipps-University Marburg Curated by ChEMBL | Assay Description Binding affinity to thrombin (unknown origin) by direct isothermal titration colorimetry | J Med Chem 58: 6960-71 (2015) BindingDB Entry DOI: 10.7270/Q26M38M6 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Asubio Medical Research Laboratories, LLC Curated by ChEMBL | Assay Description Inhibition of f11a | Bioorg Med Chem Lett 16: 5022-7 (2006) Article DOI: 10.1016/j.bmcl.2006.07.043 BindingDB Entry DOI: 10.7270/Q2PV6M5D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
