BDBM50038226 5-(2-Ethyl-2H-tetrazol-5-yl)-1,2,3,6-tetrahydro-pyridine::CHEMBL337676

SMILES: CCn1nnc(n1)C1=CCCNC1

InChI Key: InChIKey=KWCDFRUNFDIIQT-UHFFFAOYSA-N

Data: 1 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50038226   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50038226 (5-(2-Ethyl-2H-tetrazol-5-yl)-1,2,3,6-tetrahydro-py...) Show SMILES CCn1nnc(n1)C1=CCCNC1 |t:8| Show InChI InChI=1S/C8H13N5/c1-2-13-11-8(10-12-13)7-4-3-5-9-6-7/h4,9H,2-3,5-6H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description In vitro binding affinity for muscarinic M1 receptor by displacing [3H]-Pirenzepine binding on rat brain homogenate.				J Med Chem 37: 4085-99 (1995) BindingDB Entry DOI: 10.7270/Q21N8066
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50038226 (5-(2-Ethyl-2H-tetrazol-5-yl)-1,2,3,6-tetrahydro-py...) Show SMILES CCn1nnc(n1)C1=CCCNC1 |t:8| Show InChI InChI=1S/C8H13N5/c1-2-13-11-8(10-12-13)7-4-3-5-9-6-7/h4,9H,2-3,5-6H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description M2 agonist activity estimated by depression of isolated guinea pig left atrium				J Med Chem 37: 4085-99 (1995) BindingDB Entry DOI: 10.7270/Q21N8066
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Cavia porcellus)	BDBM50038226 (5-(2-Ethyl-2H-tetrazol-5-yl)-1,2,3,6-tetrahydro-py...) Show SMILES CCn1nnc(n1)C1=CCCNC1 |t:8| Show InChI InChI=1S/C8H13N5/c1-2-13-11-8(10-12-13)7-4-3-5-9-6-7/h4,9H,2-3,5-6H2,1H3	MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description In vitro ability of the compound to contract isolated guinea pig ileum was used to estimate M3 agonist effect				J Med Chem 37: 4085-99 (1995) BindingDB Entry DOI: 10.7270/Q21N8066
					More data for this Ligand-Target Pair