BDBM50038348 5,8,9,13b-Tetrahydro-6H-isoquino[1,2-a]isoquinoline-2,3-diol::CHEMBL445129

SMILES: Oc1cc2CCN3CCc4ccccc4C3c2cc1O

InChI Key: InChIKey=ORHIGFQDQVYZPJ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50038348   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A) dopamine receptor (RAT)	BDBM50038348 (5,8,9,13b-Tetrahydro-6H-isoquino[1,2-a]isoquinolin...) Show SMILES Oc1cc2CCN3CCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-9-12-6-8-18-7-5-11-3-1-2-4-13(11)17(18)14(12)10-16(15)20/h1-4,9-10,17,19-20H,5-8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Binding affinity towards dopamine receptor D1 using [3H]-SCH-23,390 was determined in rat striatal membranes				J Med Chem 37: 4317-28 (1995) Checked by Author BindingDB Entry DOI: 10.7270/Q2NC607Q
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50038348 (5,8,9,13b-Tetrahydro-6H-isoquino[1,2-a]isoquinolin...) Show SMILES Oc1cc2CCN3CCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-9-12-6-8-18-7-5-11-3-1-2-4-13(11)17(18)14(12)10-16(15)20/h1-4,9-10,17,19-20H,5-8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Binding affinity towards dopamine (D1) receptor using [3H]-spiperone was determined in rat striatal membranes				J Med Chem 37: 4317-28 (1995) Checked by Author BindingDB Entry DOI: 10.7270/Q2NC607Q
					More data for this Ligand-Target Pair