BDBM50038749 (R)-2-Pyridin-3-yl-thiazolidine-4-carboxylic acid [3-(3,4,5-trimethoxy-benzoyl)-phenyl]-amide::CHEMBL439937

SMILES: COc1cc(cc(OC)c1OC)C(=O)c1cccc(NC(=O)[C@@H]2CSC(N2)c2cccnc2)c1

InChI Key: InChIKey=IXHPJPFGFGYBPD-UBDBMELISA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038749   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet activating factor receptor (Cavia porcellus)	BDBM50038749 ((R)-2-Pyridin-3-yl-thiazolidine-4-carboxylic acid ...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)c1cccc(NC(=O)[C@@H]2CSC(N2)c2cccnc2)c1 Show InChI InChI=1S/C25H25N3O5S/c1-31-20-11-17(12-21(32-2)23(20)33-3)22(29)15-6-4-8-18(10-15)27-24(30)19-14-34-25(28-19)16-7-5-9-26-13-16/h4-13,19,25,28H,14H2,1-3H3,(H,27,30)/t19-,25?/m0/s1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligand				J Med Chem 37: 2011-32 (1994) BindingDB Entry DOI: 10.7270/Q2GH9JM7
					More data for this Ligand-Target Pair