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BDBM50038749 (R)-2-Pyridin-3-yl-thiazolidine-4-carboxylic acid [3-(3,4,5-trimethoxy-benzoyl)-phenyl]-amide::CHEMBL439937

SMILES: COc1cc(cc(OC)c1OC)C(=O)c1cccc(NC(=O)[C@@H]2CSC(N2)c2cccnc2)c1

InChI Key: InChIKey=IXHPJPFGFGYBPD-UBDBMELISA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038749   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50038749
PNG
((R)-2-Pyridin-3-yl-thiazolidine-4-carboxylic acid ...)
Show SMILES COc1cc(cc(OC)c1OC)C(=O)c1cccc(NC(=O)[C@@H]2CSC(N2)c2cccnc2)c1
Show InChI InChI=1S/C25H25N3O5S/c1-31-20-11-17(12-21(32-2)23(20)33-3)22(29)15-6-4-8-18(10-15)27-24(30)19-14-34-25(28-19)16-7-5-9-26-13-16/h4-13,19,25,28H,14H2,1-3H3,(H,27,30)/t19-,25?/m0/s1
MMDB

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PC cid
PC sid
UniChem
PubMed
1.60n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligand


J Med Chem 37: 2011-32 (1994)


BindingDB Entry DOI: 10.7270/Q2GH9JM7
More data for this
Ligand-Target Pair