new BindingDB logo
myBDB logout

BDBM50038762 (7-Methyl-1H-indol-3-yl)-((R)-2-pyridin-3-yl-thiazolidin-4-yl)-methanone::CHEMBL62219

SMILES: Cc1cccc2c(c[nH]c12)C(=O)[C@@H]1CSC(N1)c1cccnc1

InChI Key: InChIKey=REWXXQFTSVIVGK-BUSXIPJBSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038762   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50038762
PNG
((7-Methyl-1H-indol-3-yl)-((R)-2-pyridin-3-yl-thiaz...)
Show SMILES Cc1cccc2c(c[nH]c12)C(=O)[C@@H]1CSC(N1)c1cccnc1
Show InChI InChI=1S/C18H17N3OS/c1-11-4-2-6-13-14(9-20-16(11)13)17(22)15-10-23-18(21-15)12-5-3-7-19-8-12/h2-9,15,18,20-21H,10H2,1H3/t15-,18?/m0/s1
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
6.5n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligand


J Med Chem 37: 2011-32 (1994)


BindingDB Entry DOI: 10.7270/Q2GH9JM7
More data for this
Ligand-Target Pair