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BDBM50038769 3-((R)-2-Pyridin-3-yl-thiazolidine-4-carbonyl)-indole-1-carboxylic acid benzyl ester; compound with oxalic acid::CHEMBL64860

SMILES: O=C(OCc1ccccc1)n1cc(C(=O)[C@@H]2CSC(N2)c2cccnc2)c2ccccc12

InChI Key: InChIKey=BOQGBGXXEKCWEY-XEGCMXMBSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038769   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50038769
PNG
(3-((R)-2-Pyridin-3-yl-thiazolidine-4-carbonyl)-ind...)
Show SMILES O=C(OCc1ccccc1)n1cc(C(=O)[C@@H]2CSC(N2)c2cccnc2)c2ccccc12
Show InChI InChI=1S/C25H21N3O3S/c29-23(21-16-32-24(27-21)18-9-6-12-26-13-18)20-14-28(22-11-5-4-10-19(20)22)25(30)31-15-17-7-2-1-3-8-17/h1-14,21,24,27H,15-16H2/t21-,24?/m0/s1
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PC cid
PC sid
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3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligand


J Med Chem 37: 2011-32 (1994)


BindingDB Entry DOI: 10.7270/Q2GH9JM7
More data for this
Ligand-Target Pair