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BDBM50038772 6-Phenyl-3-((R)-2-pyridin-3-yl-thiazolidine-4-carbonyl)-indole-1-carboxylic acid dimethylamide::CHEMBL64621

SMILES: CN(C)C(=O)n1cc(C(=O)[C@@H]2CSC(N2)c2cccnc2)c2ccc(cc12)-c1ccccc1

InChI Key: InChIKey=WIBAMMUCSUETLG-XADRRFQNSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038772   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50038772
PNG
(6-Phenyl-3-((R)-2-pyridin-3-yl-thiazolidine-4-carb...)
Show SMILES CN(C)C(=O)n1cc(C(=O)[C@@H]2CSC(N2)c2cccnc2)c2ccc(cc12)-c1ccccc1
Show InChI InChI=1S/C26H24N4O2S/c1-29(2)26(32)30-15-21(20-11-10-18(13-23(20)30)17-7-4-3-5-8-17)24(31)22-16-33-25(28-22)19-9-6-12-27-14-19/h3-15,22,25,28H,16H2,1-2H3/t22-,25?/m0/s1
MMDB

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PC cid
PC sid
UniChem
PubMed
3.60n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligand


J Med Chem 37: 2011-32 (1994)


BindingDB Entry DOI: 10.7270/Q2GH9JM7
More data for this
Ligand-Target Pair