new BindingDB logo
myBDB logout

BDBM50038774 (R)-2-Pyridin-3-yl-thiazolidine-4-carboxylic acid (3-benzoyl-phenyl)-amide::CHEMBL303357

SMILES: O=C(Nc1cccc(c1)C(=O)c1ccccc1)[C@@H]1CSC(N1)c1cccnc1

InChI Key: InChIKey=GODKDFFNZRYHBY-YDNXMHBPSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50038774   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50038774
PNG
((R)-2-Pyridin-3-yl-thiazolidine-4-carboxylic acid ...)
Show SMILES O=C(Nc1cccc(c1)C(=O)c1ccccc1)[C@@H]1CSC(N1)c1cccnc1
Show InChI InChI=1S/C22H19N3O2S/c26-20(15-6-2-1-3-7-15)16-8-4-10-18(12-16)24-21(27)19-14-28-22(25-19)17-9-5-11-23-13-17/h1-13,19,22,25H,14H2,(H,24,27)/t19-,22?/m0/s1
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PAF binding to rabbit platelet membranes


Bioorg Med Chem Lett 3: 2729-2732 (1993)


Article DOI: 10.1016/S0960-894X(01)80753-8
BindingDB Entry DOI: 10.7270/Q2TX3F9X
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50038774
PNG
((R)-2-Pyridin-3-yl-thiazolidine-4-carboxylic acid ...)
Show SMILES O=C(Nc1cccc(c1)C(=O)c1ccccc1)[C@@H]1CSC(N1)c1cccnc1
Show InChI InChI=1S/C22H19N3O2S/c26-20(15-6-2-1-3-7-15)16-8-4-10-18(12-16)24-21(27)19-14-28-22(25-19)17-9-5-11-23-13-17/h1-13,19,22,25H,14H2,(H,24,27)/t19-,22?/m0/s1
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
7.70n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligand


J Med Chem 37: 2011-32 (1994)


BindingDB Entry DOI: 10.7270/Q2GH9JM7
More data for this
Ligand-Target Pair