new BindingDB logo
myBDB logout

BDBM50038782 2-[3-((R)-2-Pyridin-3-yl-thiazolidine-4-carbonyl)-indol-1-yl]-acetamide::CHEMBL64472

SMILES: NC(=O)Cn1cc(C(=O)[C@@H]2CSC(N2)c2cccnc2)c2ccccc12

InChI Key: InChIKey=NEMFJZVRNTYKEF-FUKCDUGKSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038782   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50038782
PNG
(2-[3-((R)-2-Pyridin-3-yl-thiazolidine-4-carbonyl)-...)
Show SMILES NC(=O)Cn1cc(C(=O)[C@@H]2CSC(N2)c2cccnc2)c2ccccc12
Show InChI InChI=1S/C19H18N4O2S/c20-17(24)10-23-9-14(13-5-1-2-6-16(13)23)18(25)15-11-26-19(22-15)12-4-3-7-21-8-12/h1-9,15,19,22H,10-11H2,(H2,20,24)/t15-,19?/m0/s1
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
5n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligand


J Med Chem 37: 2011-32 (1994)


BindingDB Entry DOI: 10.7270/Q2GH9JM7
More data for this
Ligand-Target Pair