BDBM50038789 5,6-Dimethoxy-3-((R)-2-pyridin-3-yl-thiazolidine-4-carbonyl)-indole-1-carboxylic acid dimethylamide::CHEMBL293641

SMILES: COc1cc2c(cn(C(=O)N(C)C)c2cc1OC)C(=O)[C@@H]1CSC(N1)c1cccnc1

InChI Key: InChIKey=LDEOMUXXMIHGCM-BJQOMGFOSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038789   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet activating factor receptor (Cavia porcellus)	BDBM50038789 (5,6-Dimethoxy-3-((R)-2-pyridin-3-yl-thiazolidine-4...) Show SMILES COc1cc2c(cn(C(=O)N(C)C)c2cc1OC)C(=O)[C@@H]1CSC(N1)c1cccnc1 Show InChI InChI=1S/C22H24N4O4S/c1-25(2)22(28)26-11-15(14-8-18(29-3)19(30-4)9-17(14)26)20(27)16-12-31-21(24-16)13-6-5-7-23-10-13/h5-11,16,21,24H,12H2,1-4H3/t16-,21?/m0/s1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligand				J Med Chem 37: 2011-32 (1994) BindingDB Entry DOI: 10.7270/Q2GH9JM7
					More data for this Ligand-Target Pair