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BDBM50038796 6-(4-Fluoro-phenyl)-3-((R)-2-pyridin-3-yl-thiazolidine-4-carbonyl)-indole-1-carboxylic acid dimethylamide::CHEMBL293642

SMILES: CN(C)C(=O)n1cc(C(=O)[C@@H]2CSC(N2)c2cccnc2)c2ccc(cc12)-c1ccc(F)cc1

InChI Key: InChIKey=QSDTUZPBWKSIKQ-XADRRFQNSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038796   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)		BDBM50038796
PNG
(6-(4-Fluoro-phenyl)-3-((R)-2-pyridin-3-yl-thiazoli...)
Show SMILES CN(C)C(=O)n1cc(C(=O)[C@@H]2CSC(N2)c2cccnc2)c2ccc(cc12)-c1ccc(F)cc1
Show InChI InChI=1S/C26H23FN4O2S/c1-30(2)26(33)31-14-21(24(32)22-15-34-25(29-22)18-4-3-11-28-13-18)20-10-7-17(12-23(20)31)16-5-8-19(27)9-6-16/h3-14,22,25,29H,15H2,1-2H3/t22-,25?/m0/s1
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Similars
PubMed
 9.20n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligand

J Med Chem 37: 2011-32 (1994)


BindingDB Entry DOI: 10.7270/Q2GH9JM7
More data for this
Ligand-Target Pair