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BDBM50038801 CHEMBL62830::[6-(4-Fluoro-benzyloxy)-1H-indol-3-yl]-((R)-2-pyridin-3-yl-thiazolidin-4-yl)-methanone

SMILES: Fc1ccc(COc2ccc3c(c[nH]c3c2)C(=O)[C@@H]2CSC(N2)c2cccnc2)cc1

InChI Key: InChIKey=DQNZOASLTKPJHJ-OWJIYDKWSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038801   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50038801
PNG
(CHEMBL62830 | [6-(4-Fluoro-benzyloxy)-1H-indol-3-y...)
Show SMILES Fc1ccc(COc2ccc3c(c[nH]c3c2)C(=O)[C@@H]2CSC(N2)c2cccnc2)cc1
Show InChI InChI=1S/C24H20FN3O2S/c25-17-5-3-15(4-6-17)13-30-18-7-8-19-20(12-27-21(19)10-18)23(29)22-14-31-24(28-22)16-2-1-9-26-11-16/h1-12,22,24,27-28H,13-14H2/t22-,24?/m0/s1
MMDB

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CHEMBL
PC cid
PC sid
UniChem
PubMed
1.60n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligand


J Med Chem 37: 2011-32 (1994)


BindingDB Entry DOI: 10.7270/Q2GH9JM7
More data for this
Ligand-Target Pair