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BDBM50038810 3-((R)-2-Pyridin-3-yl-thiazolidine-4-carbonyl)-indole-1-carboxylic acid diethylamide::CHEMBL293906

SMILES: CCN(CC)C(=O)n1cc(C(=O)[C@@H]2CSC(N2)c2cccnc2)c2ccccc12

InChI Key: InChIKey=JJCISVQVDBOJBQ-YMXDCFFPSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038810   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50038810
PNG
(3-((R)-2-Pyridin-3-yl-thiazolidine-4-carbonyl)-ind...)
Show SMILES CCN(CC)C(=O)n1cc(C(=O)[C@@H]2CSC(N2)c2cccnc2)c2ccccc12
Show InChI InChI=1S/C22H24N4O2S/c1-3-25(4-2)22(28)26-13-17(16-9-5-6-10-19(16)26)20(27)18-14-29-21(24-18)15-8-7-11-23-12-15/h5-13,18,21,24H,3-4,14H2,1-2H3/t18-,21?/m0/s1
MMDB

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PC cid
PC sid
UniChem
PubMed
1.40n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligand


J Med Chem 37: 2011-32 (1994)


BindingDB Entry DOI: 10.7270/Q2GH9JM7
More data for this
Ligand-Target Pair