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BDBM50038812 2,2-Dimethyl-1-[3-((R)-2-pyridin-3-yl-thiazolidine-4-carbonyl)-indol-1-yl]-propan-1-one::CHEMBL60477

SMILES: CC(C)(C)C(=O)n1cc(C(=O)[C@@H]2CSC(N2)c2cccnc2)c2ccccc12

InChI Key: InChIKey=SKFFSSPNEHZZSL-DIMJTDRSSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038812   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50038812
PNG
(2,2-Dimethyl-1-[3-((R)-2-pyridin-3-yl-thiazolidine...)
Show SMILES CC(C)(C)C(=O)n1cc(C(=O)[C@@H]2CSC(N2)c2cccnc2)c2ccccc12
Show InChI InChI=1S/C22H23N3O2S/c1-22(2,3)21(27)25-12-16(15-8-4-5-9-18(15)25)19(26)17-13-28-20(24-17)14-7-6-10-23-11-14/h4-12,17,20,24H,13H2,1-3H3/t17-,20?/m0/s1
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PC cid
PC sid
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PubMed
8.80n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligand


J Med Chem 37: 2011-32 (1994)


BindingDB Entry DOI: 10.7270/Q2GH9JM7
More data for this
Ligand-Target Pair