BDBM50038812 2,2-Dimethyl-1-[3-((R)-2-pyridin-3-yl-thiazolidine-4-carbonyl)-indol-1-yl]-propan-1-one::CHEMBL60477

SMILES: CC(C)(C)C(=O)n1cc(C(=O)[C@@H]2CSC(N2)c2cccnc2)c2ccccc12

InChI Key: InChIKey=SKFFSSPNEHZZSL-DIMJTDRSSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038812   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet activating factor receptor (Cavia porcellus)	BDBM50038812 (2,2-Dimethyl-1-[3-((R)-2-pyridin-3-yl-thiazolidine...) Show SMILES CC(C)(C)C(=O)n1cc(C(=O)[C@@H]2CSC(N2)c2cccnc2)c2ccccc12 Show InChI InChI=1S/C22H23N3O2S/c1-22(2,3)21(27)25-12-16(15-8-4-5-9-18(15)25)19(26)17-13-28-20(24-17)14-7-6-10-23-11-14/h4-12,17,20,24H,13H2,1-3H3/t17-,20?/m0/s1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligand				J Med Chem 37: 2011-32 (1994) BindingDB Entry DOI: 10.7270/Q2GH9JM7
					More data for this Ligand-Target Pair