BDBM50038835 6-(4-Fluoro-benzyloxy)-3-((R)-2-pyridin-3-yl-thiazolidine-4-carbonyl)-indole-1-carboxylic acid dimethylamide::CHEMBL291372

SMILES: CN(C)C(=O)n1cc(C(=O)[C@@H]2CSC(N2)c2cccnc2)c2ccc(OCc3ccc(F)cc3)cc12

InChI Key: InChIKey=JJYJIAAMRPWUNA-ZZHFZYNASA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038835   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet activating factor receptor (Cavia porcellus)	BDBM50038835 (6-(4-Fluoro-benzyloxy)-3-((R)-2-pyridin-3-yl-thiaz...) Show SMILES CN(C)C(=O)n1cc(C(=O)[C@@H]2CSC(N2)c2cccnc2)c2ccc(OCc3ccc(F)cc3)cc12 Show InChI InChI=1S/C27H25FN4O3S/c1-31(2)27(34)32-14-22(25(33)23-16-36-26(30-23)18-4-3-11-29-13-18)21-10-9-20(12-24(21)32)35-15-17-5-7-19(28)8-6-17/h3-14,23,26,30H,15-16H2,1-2H3/t23-,26?/m0/s1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligand				J Med Chem 37: 2011-32 (1994) BindingDB Entry DOI: 10.7270/Q2GH9JM7
					More data for this Ligand-Target Pair