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BDBM50038835 6-(4-Fluoro-benzyloxy)-3-((R)-2-pyridin-3-yl-thiazolidine-4-carbonyl)-indole-1-carboxylic acid dimethylamide::CHEMBL291372

SMILES: CN(C)C(=O)n1cc(C(=O)[C@@H]2CSC(N2)c2cccnc2)c2ccc(OCc3ccc(F)cc3)cc12

InChI Key: InChIKey=JJYJIAAMRPWUNA-ZZHFZYNASA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038835   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50038835
PNG
(6-(4-Fluoro-benzyloxy)-3-((R)-2-pyridin-3-yl-thiaz...)
Show SMILES CN(C)C(=O)n1cc(C(=O)[C@@H]2CSC(N2)c2cccnc2)c2ccc(OCc3ccc(F)cc3)cc12
Show InChI InChI=1S/C27H25FN4O3S/c1-31(2)27(34)32-14-22(25(33)23-16-36-26(30-23)18-4-3-11-29-13-18)21-10-9-20(12-24(21)32)35-15-17-5-7-19(28)8-6-17/h3-14,23,26,30H,15-16H2,1-2H3/t23-,26?/m0/s1
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PC cid
PC sid
UniChem
PubMed
1.80n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligand


J Med Chem 37: 2011-32 (1994)


BindingDB Entry DOI: 10.7270/Q2GH9JM7
More data for this
Ligand-Target Pair