BDBM50038887 2-(S)-1,2,3,4-Tetrahydro-naphthalen-2-yl-1-[(R)-2-(thiazolidine-3-carbonyl)-pyrrolidin-1-yl]-ethanone::CHEMBL65109

SMILES: O=C(C[C@H]1CCc2ccccc2C1)N1CCC[C@@H]1C(=O)N1CCSC1

InChI Key: InChIKey=QZYIRGJJFRDKBY-MAUKXSAKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038887   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50038887 (2-(S)-1,2,3,4-Tetrahydro-naphthalen-2-yl-1-[(R)-2-...) Show SMILES O=C(C[C@H]1CCc2ccccc2C1)N1CCC[C@@H]1C(=O)N1CCSC1 Show InChI InChI=1S/C20H26N2O2S/c23-19(13-15-7-8-16-4-1-2-5-17(16)12-15)22-9-3-6-18(22)20(24)21-10-11-25-14-21/h1-2,4-5,15,18H,3,6-14H2/t15-,18+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Zeria Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory activity against purified prolyl endopeptidase (PEP) from canine brain.				J Med Chem 37: 2071-8 (1994) BindingDB Entry DOI: 10.7270/Q270822J
					More data for this Ligand-Target Pair