BDBM50038917 1-[6-Chloro-4-(4-methoxy-phenyl)-quinolin-3-yl]-3-(2,4-difluoro-phenyl)-urea::CHEMBL278042

SMILES: COc1ccc(cc1)-c1c(NC(=O)Nc2ccc(F)cc2F)cnc2ccc(Cl)cc12

InChI Key: InChIKey=VTABNCCHKYTPIF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038917   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sterol O-acyltransferase, Soat (Rattus norvegicus)	BDBM50038917 (1-[6-Chloro-4-(4-methoxy-phenyl)-quinolin-3-yl]-3-...) Show SMILES COc1ccc(cc1)-c1c(NC(=O)Nc2ccc(F)cc2F)cnc2ccc(Cl)cc12 Show InChI InChI=1S/C23H16ClF2N3O2/c1-31-16-6-2-13(3-7-16)22-17-10-14(24)4-8-19(17)27-12-21(22)29-23(30)28-20-9-5-15(25)11-18(20)26/h2-12H,1H3,(H2,28,29,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	121	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomes				J Med Chem 37: 2079-84 (1994) BindingDB Entry DOI: 10.7270/Q23F4NPC
					More data for this Ligand-Target Pair