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BDBM50038958 CHEMBL63627::N-(4-Dimethylamino-benzyl)-4-sulfamoyl-benzamide

SMILES: CN(C)c1ccc(CNC(=O)c2ccc(cc2)S(N)(=O)=O)cc1

InChI Key: InChIKey=LGHBXZXZEGZRBA-UHFFFAOYSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038958   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038958
PNG
(CHEMBL63627 | N-(4-Dimethylamino-benzyl)-4-sulfamo...)
Show SMILES CN(C)c1ccc(CNC(=O)c2ccc(cc2)S(N)(=O)=O)cc1
Show InChI InChI=1S/C16H19N3O3S/c1-19(2)14-7-3-12(4-8-14)11-18-16(20)13-5-9-15(10-6-13)23(17,21)22/h3-10H,11H2,1-2H3,(H,18,20)(H2,17,21,22)
PDB
MMDB

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PC cid
PC sid
UniChem
PubMed
n/an/an/a 1.40n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)

More data for this
Ligand-Target Pair