BDBM50039037 4-(6,7-Dimethoxy-quinolin-3-yl)-phenol::CHEMBL303704

SMILES: COc1cc2cc(cnc2cc1OC)-c1ccc(O)cc1

InChI Key: InChIKey=GVQYSEHILFQSHO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50039037   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PDGFR-beta/Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50039037 (4-(6,7-Dimethoxy-quinolin-3-yl)-phenol | CHEMBL303...) Show SMILES COc1cc2cc(cnc2cc1OC)-c1ccc(O)cc1 Show InChI InChI=1S/C17H15NO3/c1-20-16-8-12-7-13(11-3-5-14(19)6-4-11)10-18-15(12)9-17(16)21-2/h3-10,19H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description Inhibition of human PDGF receptor phosphorylation; 0.02-0.03				J Med Chem 37: 2129-37 (1994) BindingDB Entry DOI: 10.7270/Q29Z93Z8
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50039037 (4-(6,7-Dimethoxy-quinolin-3-yl)-phenol | CHEMBL303...) Show SMILES COc1cc2cc(cnc2cc1OC)-c1ccc(O)cc1 Show InChI InChI=1S/C17H15NO3/c1-20-16-8-12-7-13(11-3-5-14(19)6-4-11)10-18-15(12)9-17(16)21-2/h3-10,19H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description Concentration required to inhibit phosphorylation of isolated human epidermal growth factor tyrosine kinase receptor by 50%				J Med Chem 37: 2129-37 (1994) BindingDB Entry DOI: 10.7270/Q29Z93Z8
					More data for this Ligand-Target Pair