BDBM50039042 5,7-Dimethoxy-3-thiophen-3-yl-quinoline::CHEMBL66071

SMILES: COc1cc(OC)c2cc(cnc2c1)-c1ccsc1

InChI Key: InChIKey=OOSYGDRIWJDGFV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50039042   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PDGFR-beta/Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50039042 (5,7-Dimethoxy-3-thiophen-3-yl-quinoline | CHEMBL66...) Show SMILES COc1cc(OC)c2cc(cnc2c1)-c1ccsc1 Show InChI InChI=1S/C15H13NO2S/c1-17-12-6-14-13(15(7-12)18-2)5-11(8-16-14)10-3-4-19-9-10/h3-9H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description Inhibition of human PDGF receptor phosphorylation; 0.025-0.03				J Med Chem 37: 2129-37 (1994) BindingDB Entry DOI: 10.7270/Q29Z93Z8
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50039042 (5,7-Dimethoxy-3-thiophen-3-yl-quinoline | CHEMBL66...) Show SMILES COc1cc(OC)c2cc(cnc2c1)-c1ccsc1 Show InChI InChI=1S/C15H13NO2S/c1-17-12-6-14-13(15(7-12)18-2)5-11(8-16-14)10-3-4-19-9-10/h3-9H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description Concentration required to inhibit phosphorylation of isolated human epidermal growth factor tyrosine kinase receptor by 50%				J Med Chem 37: 2129-37 (1994) BindingDB Entry DOI: 10.7270/Q29Z93Z8
					More data for this Ligand-Target Pair