BDBM50039110 S-(N-Methyl-N-hydroxycarbomyl)ethylglutathione
SMILES: CN(O)C(=O)SCC(C([NH3+])C([O-])=O)C([O-])=O
InChI Key: InChIKey=GSZKGERASYCAIM-UHFFFAOYSA-M
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glyoxalase 1 (GLO1) (Homo sapiens (Human)) | BDBM50039110 (S-(N-Methyl-N-hydroxycarbomyl)ethylglutathione) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Tested for inhibitory activity against human erythrocyte glyoxalase I | J Med Chem 37: 2161-6 (1994) BindingDB Entry DOI: 10.7270/Q2TT4RKK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glyoxalase 1 (GLO1) (Homo sapiens (Human)) | BDBM50039110 (S-(N-Methyl-N-hydroxycarbomyl)ethylglutathione) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 6.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Tested for inhibitory activity against yeast glyoxalase I | J Med Chem 37: 2161-6 (1994) BindingDB Entry DOI: 10.7270/Q2TT4RKK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glyoxalase II (Homo sapiens (Human)) | BDBM50039110 (S-(N-Methyl-N-hydroxycarbomyl)ethylglutathione) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 4.26E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Inhibition constants obtained from using the enediol analogs as competitive inhibitors for the inhibition of thehydrolysis of S-D-lactoylglutathione ... | J Med Chem 37: 2161-6 (1994) BindingDB Entry DOI: 10.7270/Q2TT4RKK | |||||||||||
More data for this Ligand-Target Pair |