BDBM50039113 S-(N-Hydroxy-N-phenylcarbamoyl)glutathione
SMILES: [NH3+]C(CCC(=O)NC(CSC(=O)N(O)c1ccccc1)C(=O)NCC([O-])=O)C([O-])=O
InChI Key: InChIKey=GAALWJSKDIUONK-UHFFFAOYSA-M
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glyoxalase 1 (GLO1) (Homo sapiens (Human)) | BDBM50039113 (S-(N-Hydroxy-N-phenylcarbamoyl)glutathione) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Tested for inhibitory activity against human erythrocyte glyoxalase I | J Med Chem 37: 2161-6 (1994) BindingDB Entry DOI: 10.7270/Q2TT4RKK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glyoxalase II (Homo sapiens (Human)) | BDBM50039113 (S-(N-Hydroxy-N-phenylcarbamoyl)glutathione) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Inhibition constant for the inhibition of the hydrolysis of S-D-lactoylglutathione by glyoxalase II | J Med Chem 37: 2161-6 (1994) BindingDB Entry DOI: 10.7270/Q2TT4RKK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glyoxalase 1 (GLO1) (Homo sapiens (Human)) | BDBM50039113 (S-(N-Hydroxy-N-phenylcarbamoyl)glutathione) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Tested for inhibitory activity against yeast glyoxalase I | J Med Chem 37: 2161-6 (1994) BindingDB Entry DOI: 10.7270/Q2TT4RKK | |||||||||||
More data for this Ligand-Target Pair |