BDBM50039520 (S)-2-((R)-2-Mercaptomethyl-3-naphthalen-1-yl-propionylamino)-3-(4-methyl-benzylsulfanyl)-propionic acid::CHEMBL82542
SMILES: Cc1ccc(CSC[C@@H](NC(=O)[C@H](CS)Cc2cccc3ccccc23)C(O)=O)cc1
InChI Key: InChIKey=PECKPZOVWLMFRH-JTHBVZDNSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neprilysin (Oryctolagus cuniculus (rabbit)) | BDBM50039520 ((S)-2-((R)-2-Mercaptomethyl-3-naphthalen-1-yl-prop...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against neutral endopeptidase (NEP) | J Med Chem 37: 2461-76 (1994) BindingDB Entry DOI: 10.7270/Q2571B20 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin-converting enzyme (Oryctolagus cuniculus) | BDBM50039520 ((S)-2-((R)-2-Mercaptomethyl-3-naphthalen-1-yl-prop...) | MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Tested in vitro for its inhibitory activity against angiotensin converting enzyme | J Med Chem 37: 2461-76 (1994) BindingDB Entry DOI: 10.7270/Q2571B20 | |||||||||||
More data for this Ligand-Target Pair |