BDBM50039655 5,7-Dimethoxy-3-pyridin-4-yl-quinoline::CHEMBL68423

SMILES: COc1cc(OC)c2cc(cnc2c1)-c1ccncc1

InChI Key: InChIKey=HBXDLZBPKJEWHZ-UHFFFAOYSA-N

Data: 1 KI  4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50039655   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PDGFR-beta/Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50039655 (5,7-Dimethoxy-3-pyridin-4-yl-quinoline | CHEMBL684...) Show SMILES COc1cc(OC)c2cc(cnc2c1)-c1ccncc1 Show InChI InChI=1S/C16H14N2O2/c1-19-13-8-15-14(16(9-13)20-2)7-12(10-18-15)11-3-5-17-6-4-11/h3-10H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sterling Winthrop Pharmaceuticals Research Division Curated by ChEMBL					Assay Description Inhibition of PDGF-stimulated autophosphorylation of PDGF-receptor				J Med Chem 37: 2627-9 (1994) BindingDB Entry DOI: 10.7270/Q2CR5SDD
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50039655 (5,7-Dimethoxy-3-pyridin-4-yl-quinoline | CHEMBL684...) Show SMILES COc1cc(OC)c2cc(cnc2c1)-c1ccncc1 Show InChI InChI=1S/C16H14N2O2/c1-19-13-8-15-14(16(9-13)20-2)7-12(10-18-15)11-3-5-17-6-4-11/h3-10H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sterling Winthrop Pharmaceuticals Research Division Curated by ChEMBL					Assay Description Inhibition of Epidermal growth factor receptor tyrosine kinase				J Med Chem 37: 2627-9 (1994) BindingDB Entry DOI: 10.7270/Q2CR5SDD
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50039655 (5,7-Dimethoxy-3-pyridin-4-yl-quinoline | CHEMBL684...) Show SMILES COc1cc(OC)c2cc(cnc2c1)-c1ccncc1 Show InChI InChI=1S/C16H14N2O2/c1-19-13-8-15-14(16(9-13)20-2)7-12(10-18-15)11-3-5-17-6-4-11/h3-10H,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sterling Winthrop Pharmaceuticals Research Division Curated by ChEMBL					Assay Description Inhibition of p56 lck kinase				J Med Chem 37: 2627-9 (1994) BindingDB Entry DOI: 10.7270/Q2CR5SDD
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50039655 (5,7-Dimethoxy-3-pyridin-4-yl-quinoline | CHEMBL684...) Show SMILES COc1cc(OC)c2cc(cnc2c1)-c1ccncc1 Show InChI InChI=1S/C16H14N2O2/c1-19-13-8-15-14(16(9-13)20-2)7-12(10-18-15)11-3-5-17-6-4-11/h3-10H,1-2H3	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sterling Winthrop Pharmaceuticals Research Division Curated by ChEMBL					Assay Description Inhibition of erbB2 receptor				J Med Chem 37: 2627-9 (1994) BindingDB Entry DOI: 10.7270/Q2CR5SDD
					More data for this Ligand-Target Pair
PDGFR-beta/Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50039655 (5,7-Dimethoxy-3-pyridin-4-yl-quinoline | CHEMBL684...) Show SMILES COc1cc(OC)c2cc(cnc2c1)-c1ccncc1 Show InChI InChI=1S/C16H14N2O2/c1-19-13-8-15-14(16(9-13)20-2)7-12(10-18-15)11-3-5-17-6-4-11/h3-10H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Sterling Winthrop Pharmaceuticals Research Division Curated by ChEMBL					Assay Description Inhibition of Platelet-derived growth factor receptor tyrosine kinase				J Med Chem 37: 2627-9 (1994) BindingDB Entry DOI: 10.7270/Q2CR5SDD
					More data for this Ligand-Target Pair