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BDBM50040077 5-Iodo-2,3-dihydro-benzofuran-7-carboxylic acid [1-(4-fluoro-benzyl)-pyrrolidin-2-ylmethyl]-amide (IBF)::CHEMBL431384

SMILES: Fc1ccc(CN2CCC[C@H]2CNC(=O)c2cc(I)cc3CCOc23)cc1

InChI Key: InChIKey=YLNWTPBWQPADOJ-SFHVURJKSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50040077   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50040077
PNG
(5-Iodo-2,3-dihydro-benzofuran-7-carboxylic acid [1...)
Show SMILES Fc1ccc(CN2CCC[C@H]2CNC(=O)c2cc(I)cc3CCOc23)cc1
Show InChI InChI=1S/C21H22FIN2O2/c22-16-5-3-14(4-6-16)13-25-8-1-2-18(25)12-24-21(26)19-11-17(23)10-15-7-9-27-20(15)19/h3-6,10-11,18H,1-2,7-9,12-13H2,(H,24,26)/t18-/m0/s1
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Similars
PubMed
 0.106n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition constant against dopamine receptor D2 in rat

J Med Chem 36: 221-8 (1993)


BindingDB Entry DOI: 10.7270/Q2TT4Q10
More data for this
Ligand-Target Pair