BDBM50040299 CHEMBL410783::cyclopropylbenzene(CO)His-Trp-Ala-Val-DAla-His-DPro(psi)Phe-NH2

SMILES: CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)C1C[C@@H]1c1ccccc1)C(=O)N[C@H](C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@@H]1CN[C@@H](Cc1ccccc1)C(N)=O

InChI Key: InChIKey=PRYZTLPJFLNJDS-MKJRTOFZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50040299   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gastrin releasing peptide receptor (MOUSE)	BDBM50040299 (CHEMBL410783 | cyclopropylbenzene(CO)His-Trp-Ala-V...) Show SMILES CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)C1C[C@@H]1c1ccccc1)C(=O)N[C@H](C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@@H]1CN[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C58H72N14O8/c1-33(2)50(57(79)67-34(3)52(74)70-49(25-40-29-61-32-65-40)58(80)72-21-13-18-41(72)30-63-46(51(59)73)22-36-14-7-5-8-15-36)71-53(75)35(4)66-55(77)47(23-38-27-62-45-20-12-11-19-42(38)45)69-56(78)48(24-39-28-60-31-64-39)68-54(76)44-26-43(44)37-16-9-6-10-17-37/h5-12,14-17,19-20,27-29,31-35,41,43-44,46-50,62-63H,13,18,21-26,30H2,1-4H3,(H2,59,73)(H,60,64)(H,61,65)(H,66,77)(H,67,79)(H,68,76)(H,69,78)(H,70,74)(H,71,75)/t34-,35+,41-,43-,44?,46+,47+,48+,49+,50+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Company Curated by ChEMBL					Assay Description The ability of the peptide to inhibit the binding of 50 pM [125I]-Gastrin releasing peptide to intact S-3T3 cells				J Med Chem 37: 439-45 (1994) BindingDB Entry DOI: 10.7270/Q2ST7NXN
					More data for this Ligand-Target Pair
Gastrin releasing peptide receptor (MOUSE)	BDBM50040299 (CHEMBL410783 | cyclopropylbenzene(CO)His-Trp-Ala-V...) Show SMILES CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)C1C[C@@H]1c1ccccc1)C(=O)N[C@H](C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@@H]1CN[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C58H72N14O8/c1-33(2)50(57(79)67-34(3)52(74)70-49(25-40-29-61-32-65-40)58(80)72-21-13-18-41(72)30-63-46(51(59)73)22-36-14-7-5-8-15-36)71-53(75)35(4)66-55(77)47(23-38-27-62-45-20-12-11-19-42(38)45)69-56(78)48(24-39-28-60-31-64-39)68-54(76)44-26-43(44)37-16-9-6-10-17-37/h5-12,14-17,19-20,27-29,31-35,41,43-44,46-50,62-63H,13,18,21-26,30H2,1-4H3,(H2,59,73)(H,60,64)(H,61,65)(H,66,77)(H,67,79)(H,68,76)(H,69,78)(H,70,74)(H,71,75)/t34-,35+,41-,43-,44?,46+,47+,48+,49+,50+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.0490	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Company Curated by ChEMBL					Assay Description Ability of peptide to inhibit binding of 10 pM [125I]-gastrin releasing peptide to S-3T3 cell membrane.				J Med Chem 37: 439-45 (1994) BindingDB Entry DOI: 10.7270/Q2ST7NXN
					More data for this Ligand-Target Pair