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SMILES: OC(=O)c1ccc(NC(=O)C(Cc2ccc(cc2)-c2ccccc2)NCP(O)(O)=O)cc1

InChI Key: InChIKey=JDKUZYYBXRCCFM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50040406   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Rattus norvegicus (Rat))		BDBM50040406
PNG
(4-[3-Biphenyl-4-yl-2-(phosphonomethyl-amino)-propi...)
Show SMILES OC(=O)c1ccc(NC(=O)C(Cc2ccc(cc2)-c2ccccc2)NCP(O)(O)=O)cc1
Show InChI InChI=1S/C23H23N2O6P/c26-22(25-20-12-10-19(11-13-20)23(27)28)21(24-15-32(29,30)31)14-16-6-8-18(9-7-16)17-4-2-1-3-5-17/h1-13,21,24H,14-15H2,(H,25,26)(H,27,28)(H2,29,30,31)
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n/an/a 10n/an/an/an/an/an/a



CIBA-GEIGY Corporation

Curated by ChEMBL


Assay Description
In vitro inhibition of Neutral endopeptidase (NEP) enzyme

J Med Chem 37: 498-511 (1994)


BindingDB Entry DOI: 10.7270/Q2H70GF9
More data for this
Ligand-Target Pair