BDBM50040951 CHEMBL3354402

SMILES: Fc1ccc(C(=O)n2c3ccccc3c3nnc(SCc4ccccc4C#N)nc23)c(c1)C(F)(F)F

InChI Key: InChIKey=WZICSLPEAIAEJQ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50040951   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50040951 (CHEMBL3354402) Show SMILES Fc1ccc(C(=O)n2c3ccccc3c3nnc(SCc4ccccc4C#N)nc23)c(c1)C(F)(F)F Show InChI InChI=1S/C25H13F4N5OS/c26-16-9-10-17(19(11-16)25(27,28)29)23(35)34-20-8-4-3-7-18(20)21-22(34)31-24(33-32-21)36-13-15-6-2-1-5-14(15)12-30/h1-11H,13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Agonist activity at human CB2R expressed in CHO cells assessed as reduction in forskolin-induced cAMP accumulation by beta-galactosidase based comple...				Bioorg Med Chem 23: 241-63 (2014) Article DOI: 10.1016/j.bmc.2014.11.002 BindingDB Entry DOI: 10.7270/Q2930VS3
					More data for this Ligand-Target Pair