BDBM50041071 (2-Mercaptomethyl-3-phenyl-butyrylamino)-acetic acid::CHEMBL273748
SMILES: CC(C(CS)C(=O)NCC(O)=O)c1ccccc1
InChI Key: InChIKey=DWVAKFQCCFXMLC-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neprilysin (Homo sapiens (Human)) | BDBM50041071 ((2-Mercaptomethyl-3-phenyl-butyrylamino)-acetic ac...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description In vivo inhibitory potency against neutral endopeptidase by displacement of [3H]-HACBOGly binding in mouse kidney | J Med Chem 37: 1070-83 (1994) BindingDB Entry DOI: 10.7270/Q26W995T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin-converting enzyme (Mus musculus) | BDBM50041071 ((2-Mercaptomethyl-3-phenyl-butyrylamino)-acetic ac...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Inhibitory potency against angiotensin converting enzyme by displacement of [3H]-trandolaprilate binding in mouse lung | J Med Chem 37: 1070-83 (1994) BindingDB Entry DOI: 10.7270/Q26W995T | |||||||||||
More data for this Ligand-Target Pair |