BDBM50041337 3-[4-(2-Bromo-benzenesulfonylaminocarbonyl)-2-methoxy-benzyl]-1-methyl-1H-indole-5-carboxylic acid (2-ethyl-4,4,4-trifluoro-butyl)-amide::CHEMBL26002

SMILES: CCC(CNC(=O)c1ccc2n(C)cc(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3Br)c2c1)CC(F)(F)F

InChI Key: InChIKey=XAFQAWUYPZQDBU-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50041337   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041337 (3-[4-(2-Bromo-benzenesulfonylaminocarbonyl)-2-meth...) Show SMILES CCC(CNC(=O)c1ccc2n(C)cc(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3Br)c2c1)CC(F)(F)F Show InChI InChI=1S/C31H31BrF3N3O5S/c1-4-19(16-31(33,34)35)17-36-29(39)21-11-12-26-24(14-21)23(18-38(26)2)13-20-9-10-22(15-27(20)43-3)30(40)37-44(41,42)28-8-6-5-7-25(28)32/h5-12,14-15,18-19H,4,13,16-17H2,1-3H3,(H,36,39)(H,37,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair