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BDBM50041456 CHEMBL3357377

SMILES: CN1CCC(CS(=O)(=O)c2ccc3n(CC4CC4)c(CC(C)(C)C)nc3c2)CC1

InChI Key: InChIKey=LXSZFACKDXQTEW-UHFFFAOYSA-N

Data: 1 EC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50041456   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041456
PNG
(CHEMBL3357377)
Show SMILES CN1CCC(CS(=O)(=O)c2ccc3n(CC4CC4)c(CC(C)(C)C)nc3c2)CC1
Show InChI InChI=1S/C23H35N3O2S/c1-23(2,3)14-22-24-20-13-19(7-8-21(20)26(22)15-17-5-6-17)29(27,28)16-18-9-11-25(4)12-10-18/h7-8,13,17-18H,5-6,9-12,14-16H2,1-4H3
PDB

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PC cid
PC sid
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Article
PubMed
n/an/an/an/a 209n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair