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BDBM50041471 CHEMBL30758::N-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-4-nitro-N-pyridin-2-yl-benzamide

SMILES: COc1ccccc1N1CCN(CCN(C(=O)c2ccc(cc2)[N+]([O-])=O)c2ccccn2)CC1

InChI Key: InChIKey=QWAMQPRHXWOEJC-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50041471   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50041471
PNG
(CHEMBL30758 | N-{2-[4-(2-Methoxy-phenyl)-piperazin...)
Show SMILES COc1ccccc1N1CCN(CCN(C(=O)c2ccc(cc2)[N+]([O-])=O)c2ccccn2)CC1
Show InChI InChI=1S/C25H27N5O4/c1-34-23-7-3-2-6-22(23)28-17-14-27(15-18-28)16-19-29(24-8-4-5-13-26-24)25(31)20-9-11-21(12-10-20)30(32)33/h2-13H,14-19H2,1H3
KEGG

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CHEMBL
PC cid
PC sid
UniChem
PubMed
1.60n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of binding of [125I]8-OH-PIPAT ligand to 5-hydroxytryptamine 1A receptor of rat hippocampal homogenates


J Med Chem 37: 1406-7 (1994)


BindingDB Entry DOI: 10.7270/Q29Z95JQ
More data for this
Ligand-Target Pair