BDBM50041471 CHEMBL30758::N-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-4-nitro-N-pyridin-2-yl-benzamide

SMILES: COc1ccccc1N1CCN(CCN(C(=O)c2ccc(cc2)[N+]([O-])=O)c2ccccn2)CC1

InChI Key: InChIKey=QWAMQPRHXWOEJC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50041471   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50041471 (CHEMBL30758 | N-{2-[4-(2-Methoxy-phenyl)-piperazin...) Show SMILES COc1ccccc1N1CCN(CCN(C(=O)c2ccc(cc2)[N+]([O-])=O)c2ccccn2)CC1 Show InChI InChI=1S/C25H27N5O4/c1-34-23-7-3-2-6-22(23)28-17-14-27(15-18-28)16-19-29(24-8-4-5-13-26-24)25(31)20-9-11-21(12-10-20)30(32)33/h2-13H,14-19H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of binding of [125I]8-OH-PIPAT ligand to 5-hydroxytryptamine 1A receptor of rat hippocampal homogenates				J Med Chem 37: 1406-7 (1994) BindingDB Entry DOI: 10.7270/Q29Z95JQ
					More data for this Ligand-Target Pair