Found 4 hits for monomerid = 50041558 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Neurokinin 1 receptor
(Homo sapiens (Human)) | BDBM50041558
(CHEMBL2042018)Show InChI InChI=1S/C17H18N2O3/c18-16(20)15(11-13-7-3-1-4-8-13)19-17(21)22-12-14-9-5-2-6-10-14/h1-10,15H,11-12H2,(H2,18,20)(H,19,21)/t15-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Displacement of [3H]-SP1-7 from NK1 receptor (unknown origin) by scintillation counting analysis |
ACS Med Chem Lett 5: 1272-7 (2014)
Article DOI: 10.1021/ml5002954 BindingDB Entry DOI: 10.7270/Q2Q52R7V |
More data for this Ligand-Target Pair | |
Neurokinin 1 receptor
(Rattus norvegicus (rat)) | BDBM50041558
(CHEMBL2042018)Show InChI InChI=1S/C17H18N2O3/c18-16(20)15(11-13-7-3-1-4-8-13)19-17(21)22-12-14-9-5-2-6-10-14/h1-10,15H,11-12H2,(H2,18,20)(H,19,21)/t15-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Displacement of [3H]SP1-7 from NK1 receptor in Sprague-Dawley rat spinal cord membranes after 60 mins by scintillation counting method |
Bioorg Med Chem Lett 28: 2446-2450 (2018)
Article DOI: 10.1016/j.bmcl.2018.06.009 BindingDB Entry DOI: 10.7270/Q2QF8WCB |
More data for this Ligand-Target Pair | |
Neurokinin 1 receptor
(Homo sapiens (Human)) | BDBM50041558
(CHEMBL2042018)Show InChI InChI=1S/C17H18N2O3/c18-16(20)15(11-13-7-3-1-4-8-13)19-17(21)22-12-14-9-5-2-6-10-14/h1-10,15H,11-12H2,(H2,18,20)(H,19,21)/t15-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Binding affinity to NK1 receptor (unknown origin) |
ACS Med Chem Lett 5: 1272-7 (2014)
Article DOI: 10.1021/ml5002954 BindingDB Entry DOI: 10.7270/Q2Q52R7V |
More data for this Ligand-Target Pair | |
Neurokinin 1 receptor
(Homo sapiens (Human)) | BDBM50041558
(CHEMBL2042018)Show InChI InChI=1S/C17H18N2O3/c18-16(20)15(11-13-7-3-1-4-8-13)19-17(21)22-12-14-9-5-2-6-10-14/h1-10,15H,11-12H2,(H2,18,20)(H,19,21)/t15-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Displacement of [3H]-SP1-7 from NK1 receptor (unknown origin) by scintillation counting analysis |
ACS Med Chem Lett 5: 1272-7 (2014)
Article DOI: 10.1021/ml5002954 BindingDB Entry DOI: 10.7270/Q2Q52R7V |
More data for this Ligand-Target Pair | |