BDBM50041606 CHEMBL3358432

SMILES: CCc1ncccc1Oc1cc(CC2CCCCC2)cnc1NC(=O)NC

InChI Key: InChIKey=LDRZWXMZIPLJON-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50041606   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50041606 (CHEMBL3358432) Show SMILES CCc1ncccc1Oc1cc(CC2CCCCC2)cnc1NC(=O)NC Show InChI InChI=1S/C21H28N4O2/c1-3-17-18(10-7-11-23-17)27-19-13-16(12-15-8-5-4-6-9-15)14-24-20(19)25-21(26)22-2/h7,10-11,13-15H,3-6,8-9,12H2,1-2H3,(H2,22,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Activation of human recombinant Glucokinase measured over 5 mins by G6-PD coupled assay in presence of 5 mM glucose				ACS Med Chem Lett 5: 1284-9 (2014) Article DOI: 10.1021/ml500341w BindingDB Entry DOI: 10.7270/Q2KD20JZ
					More data for this Ligand-Target Pair