BDBM50041849 3-(Bicyclo[2.2.1]hept-2-yloxy)-N-(3,5-dichloro-pyridin-4-yl)-4-methoxy-benzamide::CHEMBL296477

SMILES: COc1ccc(cc1OC1CC2CCC1C2)C(=O)Nc1c(Cl)cncc1Cl

InChI Key: InChIKey=AOGQPQXZFOWMDY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50041849   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4A (Sus scrofa)	BDBM50041849 (3-(Bicyclo[2.2.1]hept-2-yloxy)-N-(3,5-dichloro-pyr...) Show SMILES COc1ccc(cc1OC1CC2CCC1C2)C(=O)Nc1c(Cl)cncc1Cl |TLB:8:9:15:13.12| Show InChI InChI=1S/C20H20Cl2N2O3/c1-26-16-5-4-13(20(25)24-19-14(21)9-23-10-15(19)22)8-18(16)27-17-7-11-2-3-12(17)6-11/h4-5,8-12,17H,2-3,6-7H2,1H3,(H,23,24,25)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description Inhibitory potency against pig aortic PDE IV				J Med Chem 37: 1696-703 (1994) BindingDB Entry DOI: 10.7270/Q2CF9P5F
					More data for this Ligand-Target Pair
Phosphodiesterase 4A (Sus scrofa)	BDBM50041849 (3-(Bicyclo[2.2.1]hept-2-yloxy)-N-(3,5-dichloro-pyr...) Show SMILES COc1ccc(cc1OC1CC2CCC1C2)C(=O)Nc1c(Cl)cncc1Cl |TLB:8:9:15:13.12| Show InChI InChI=1S/C20H20Cl2N2O3/c1-26-16-5-4-13(20(25)24-19-14(21)9-23-10-15(19)22)8-18(16)27-17-7-11-2-3-12(17)6-11/h4-5,8-12,17H,2-3,6-7H2,1H3,(H,23,24,25)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description Inhibitory potency against pig aortic PDE IV				J Med Chem 37: 1696-703 (1994) BindingDB Entry DOI: 10.7270/Q2CF9P5F
					More data for this Ligand-Target Pair