BDBM50042469 1-(4-Dimethylamino-but-2-ynyl)-3-methyl-pyrrolidin-2-one::CHEMBL119615

SMILES: C[C@@H]1CCN(CC#CCN(C)C)C1=O

InChI Key: InChIKey=ZLYDESMUNQSKFD-SNVBAGLBSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50042469   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50042469 (1-(4-Dimethylamino-but-2-ynyl)-3-methyl-pyrrolidin...) Show SMILES C[C@@H]1CCN(CC#CCN(C)C)C1=O Show InChI InChI=1S/C11H18N2O/c1-10-6-9-13(11(10)14)8-5-4-7-12(2)3/h10H,6-9H2,1-3H3/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Division of American Cyanamid Company Curated by ChEMBL					Assay Description Binding affinity at [3H]CD radiolabeled muscarinic M2 receptor in rat cortex.				J Med Chem 36: 3533-41 (1994) BindingDB Entry DOI: 10.7270/Q28916GB
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50042469 (1-(4-Dimethylamino-but-2-ynyl)-3-methyl-pyrrolidin...) Show SMILES C[C@@H]1CCN(CC#CCN(C)C)C1=O Show InChI InChI=1S/C11H18N2O/c1-10-6-9-13(11(10)14)8-5-4-7-12(2)3/h10H,6-9H2,1-3H3/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Division of American Cyanamid Company Curated by ChEMBL					Assay Description Binding affinity at [3H]CD radiolabeled muscarinic M2 receptor in rat cortex.				J Med Chem 36: 3533-41 (1994) BindingDB Entry DOI: 10.7270/Q28916GB
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50042469 (1-(4-Dimethylamino-but-2-ynyl)-3-methyl-pyrrolidin...) Show SMILES C[C@@H]1CCN(CC#CCN(C)C)C1=O Show InChI InChI=1S/C11H18N2O/c1-10-6-9-13(11(10)14)8-5-4-7-12(2)3/h10H,6-9H2,1-3H3/t10-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Division of American Cyanamid Company Curated by ChEMBL					Assay Description Binding affinity at [3H]PZ radiolabeled muscarinic M1 receptor in rat cortex.				J Med Chem 36: 3533-41 (1994) BindingDB Entry DOI: 10.7270/Q28916GB
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50042469 (1-(4-Dimethylamino-but-2-ynyl)-3-methyl-pyrrolidin...) Show SMILES C[C@@H]1CCN(CC#CCN(C)C)C1=O Show InChI InChI=1S/C11H18N2O/c1-10-6-9-13(11(10)14)8-5-4-7-12(2)3/h10H,6-9H2,1-3H3/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Division of American Cyanamid Company Curated by ChEMBL					Assay Description Binding affinity at [3H]QNB radiolabeled muscarinic M2 receptor in rat cortex.				J Med Chem 36: 3533-41 (1994) BindingDB Entry DOI: 10.7270/Q28916GB
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50042469 (1-(4-Dimethylamino-but-2-ynyl)-3-methyl-pyrrolidin...) Show SMILES C[C@@H]1CCN(CC#CCN(C)C)C1=O Show InChI InChI=1S/C11H18N2O/c1-10-6-9-13(11(10)14)8-5-4-7-12(2)3/h10H,6-9H2,1-3H3/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Division of American Cyanamid Company Curated by ChEMBL					Assay Description Binding affinity at [3H]QNB radiolabeled muscarinic M2 receptor in rat heart.				J Med Chem 36: 3533-41 (1994) BindingDB Entry DOI: 10.7270/Q28916GB
					More data for this Ligand-Target Pair