BDBM50042544 5-Butyl-2-(2-nitro-phenyl)-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2H-pyrazole-3-carboxylic acid::CHEMBL93547

SMILES: CCCCc1nn(c(C(O)=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)-c1ccccc1[N+]([O-])=O

InChI Key: InChIKey=QBAIFEHUMQOWLP-UHFFFAOYSA-N

Data: 1 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50042544   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renal dipeptidase (GUINEA PIG)	BDBM50042544 (5-Butyl-2-(2-nitro-phenyl)-4-[2'-(1H-tetrazol-5-yl...) Show SMILES CCCCc1nn(c(C(O)=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)-c1ccccc1[N+]([O-])=O Show InChI InChI=1S/C28H25N7O4/c1-2-3-10-23-22(26(28(36)37)34(31-23)24-11-6-7-12-25(24)35(38)39)17-18-13-15-19(16-14-18)20-8-4-5-9-21(20)27-29-32-33-30-27/h4-9,11-16H,2-3,10,17H2,1H3,(H,36,37)(H,29,30,32,33)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.40E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro apparent inhibition constant of porcine renal Dehydropeptidase-1.				Bioorg Med Chem Lett 9: 2741-6 (1999) BindingDB Entry DOI: 10.7270/Q24Q7T6C
					More data for this Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor (RABBIT)	BDBM50042544 (5-Butyl-2-(2-nitro-phenyl)-4-[2'-(1H-tetrazol-5-yl...) Show SMILES CCCCc1nn(c(C(O)=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)-c1ccccc1[N+]([O-])=O Show InChI InChI=1S/C28H25N7O4/c1-2-3-10-23-22(26(28(36)37)34(31-23)24-11-6-7-12-25(24)35(38)39)17-18-13-15-19(16-14-18)20-8-4-5-9-21(20)27-29-32-33-30-27/h4-9,11-16H,2-3,10,17H2,1H3,(H,36,37)(H,29,30,32,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Evaluation of Angiotensin II antagonistic activity by displacement of [125I]-Sar Ile-AII at the rabbit aorta Angiotensin II receptor, type 1				J Med Chem 36: 3595-605 (1994) BindingDB Entry DOI: 10.7270/Q25Q4V5H
					More data for this Ligand-Target Pair
Beta-lactamase type II (Bacteroides fragilis)	BDBM50042544 (5-Butyl-2-(2-nitro-phenyl)-4-[2'-(1H-tetrazol-5-yl...) Show SMILES CCCCc1nn(c(C(O)=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)-c1ccccc1[N+]([O-])=O Show InChI InChI=1S/C28H25N7O4/c1-2-3-10-23-22(26(28(36)37)34(31-23)24-11-6-7-12-25(24)35(38)39)17-18-13-15-19(16-14-18)20-8-4-5-9-21(20)27-29-32-33-30-27/h4-9,11-16H,2-3,10,17H2,1H3,(H,36,37)(H,29,30,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of metallo-beta-lactamase (MBL) from Bacteroides fragilis.				Bioorg Med Chem Lett 9: 2741-6 (1999) BindingDB Entry DOI: 10.7270/Q24Q7T6C
					More data for this Ligand-Target Pair
metallo-beta-lactamase IMP-1 (Pseudomonas aeruginosa)	BDBM50042544 (5-Butyl-2-(2-nitro-phenyl)-4-[2'-(1H-tetrazol-5-yl...) Show SMILES CCCCc1nn(c(C(O)=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)-c1ccccc1[N+]([O-])=O Show InChI InChI=1S/C28H25N7O4/c1-2-3-10-23-22(26(28(36)37)34(31-23)24-11-6-7-12-25(24)35(38)39)17-18-13-15-19(16-14-18)20-8-4-5-9-21(20)27-29-32-33-30-27/h4-9,11-16H,2-3,10,17H2,1H3,(H,36,37)(H,29,30,32,33)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of metallo-beta-lactamase (MBL) from Pseudomonas aeruginosa mediated by the plasmid-borne IMP-1 enzyme.				Bioorg Med Chem Lett 9: 2741-6 (1999) BindingDB Entry DOI: 10.7270/Q24Q7T6C
					More data for this Ligand-Target Pair