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SMILES: COc1ccccc1N1CCN(CCCc2cn(nn2)-c2ccccc2O)CC1

InChI Key: InChIKey=GEGLEQALPLAWHZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50042728   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50042728 (CHEMBL3353915) Show SMILES COc1ccccc1N1CCN(CCCc2cn(nn2)-c2ccccc2O)CC1 Show InChI InChI=1S/C22H27N5O2/c1-29-22-11-5-3-9-20(22)26-15-13-25(14-16-26)12-6-7-18-17-27(24-23-18)19-8-2-4-10-21(19)28/h2-5,8-11,17,28H,6-7,12-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description Displacement of of [125I]-IABN from human D3 receptor expressed in HEK293 cell membranes after 60 mins by filtration binding assay				Bioorg Med Chem Lett 25: 519-23 (2015) Article DOI: 10.1016/j.bmcl.2014.12.023 BindingDB Entry DOI: 10.7270/Q27W6DS9
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50042728 (CHEMBL3353915) Show SMILES COc1ccccc1N1CCN(CCCc2cn(nn2)-c2ccccc2O)CC1 Show InChI InChI=1S/C22H27N5O2/c1-29-22-11-5-3-9-20(22)26-15-13-25(14-16-26)12-6-7-18-17-27(24-23-18)19-8-2-4-10-21(19)28/h2-5,8-11,17,28H,6-7,12-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description Displacement of of [125I]-IABN from human D2 long receptor expressed in HEK293 cell membranes after 60 mins by filtration binding assay				Bioorg Med Chem Lett 25: 519-23 (2015) Article DOI: 10.1016/j.bmcl.2014.12.023 BindingDB Entry DOI: 10.7270/Q27W6DS9
					More data for this Ligand-Target Pair