BDBM50042737 CHEMBL121891::[4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2,6-dipropyl-phenoxy]-o-tolyl-acetic acid

SMILES: CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(O)=O)c1ccccc1C

InChI Key: InChIKey=ITKQYYFEYRLELL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50042737   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II AT2 (RAT)	BDBM50042737 (CHEMBL121891 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,...) Show SMILES CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(O)=O)c1ccccc1C Show InChI InChI=1S/C32H39N3O3/c1-7-12-24-17-23(19-35-27(9-3)34-28-21(5)16-22(6)33-31(28)35)18-25(13-8-2)29(24)38-30(32(36)37)26-15-11-10-14-20(26)4/h10-11,14-18,30H,7-9,12-13,19H2,1-6H3,(H,36,37)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [1251][Sar1,IIe8]AII from rat midbrain angiotensin II (AT2) receptor				J Med Chem 36: 3738-42 (1994) BindingDB Entry DOI: 10.7270/Q2J1027W
					More data for this Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor (RABBIT)	BDBM50042737 (CHEMBL121891 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,...) Show SMILES CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(O)=O)c1ccccc1C Show InChI InChI=1S/C32H39N3O3/c1-7-12-24-17-23(19-35-27(9-3)34-28-21(5)16-22(6)33-31(28)35)18-25(13-8-2)29(24)38-30(32(36)37)26-15-11-10-14-20(26)4/h10-11,14-18,30H,7-9,12-13,19H2,1-6H3,(H,36,37)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [1251][Sar1,IIe8]AII from rabbit aorta Angiotensin II receptor, type 1				J Med Chem 36: 3738-42 (1994) BindingDB Entry DOI: 10.7270/Q2J1027W
					More data for this Ligand-Target Pair