BDBM50042807 2-Amino-7-[1-(3-chloro-phenyl)-3-hydroxy-propyl]-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one::CHEMBL331949

SMILES: Nc1nc2c(c[nH]c2c(=O)[nH]1)C(CCO)c1cccc(Cl)c1

InChI Key: InChIKey=ZKNDJBRLXZZYRL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50042807   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50042807 (2-Amino-7-[1-(3-chloro-phenyl)-3-hydroxy-propyl]-3...) Show SMILES Nc1nc2c(c[nH]c2c(=O)[nH]1)C(CCO)c1cccc(Cl)c1 Show InChI InChI=1S/C15H15ClN4O2/c16-9-3-1-2-8(6-9)10(4-5-21)11-7-18-13-12(11)19-15(17)20-14(13)22/h1-3,6-7,10,18,21H,4-5H2,(H3,17,19,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
BioCryst Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4				J Med Chem 36: 3771-83 (1994) BindingDB Entry DOI: 10.7270/Q23J3DKS
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50042807 (2-Amino-7-[1-(3-chloro-phenyl)-3-hydroxy-propyl]-3...) Show SMILES Nc1nc2c(c[nH]c2c(=O)[nH]1)C(CCO)c1cccc(Cl)c1 Show InChI InChI=1S/C15H15ClN4O2/c16-9-3-1-2-8(6-9)10(4-5-21)11-7-18-13-12(11)19-15(17)20-14(13)22/h1-3,6-7,10,18,21H,4-5H2,(H3,17,19,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
BioCryst Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4				J Med Chem 36: 3771-83 (1994) BindingDB Entry DOI: 10.7270/Q23J3DKS
					More data for this Ligand-Target Pair