null

SMILES: COc1ccc(F)c(c1)S(=O)(=O)Nc1ccc(cc1)-c1nc(O[C@H]2CC[C@H](O)CC2)c2c(C)n[nH]c2n1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043020   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Sgk1 (Homo sapiens (Human))	BDBM50043020 (CHEMBL3355030) Show SMILES COc1ccc(F)c(c1)S(=O)(=O)Nc1ccc(cc1)-c1nc(O[C@H]2CC[C@H](O)CC2)c2c(C)n[nH]c2n1 |r,wU:23.24,wD:26.28,(46.54,-10.36,;45.77,-11.7,;46.55,-13.04,;45.79,-14.37,;46.56,-15.69,;48.1,-15.7,;48.87,-17.03,;48.87,-14.36,;48.1,-13.03,;50.41,-14.36,;51.74,-15.13,;50.41,-15.9,;51.18,-13.03,;52.72,-13.03,;53.49,-14.38,;55.03,-14.38,;55.81,-13.05,;55.03,-11.7,;53.49,-11.71,;57.34,-13.05,;58.11,-11.72,;59.65,-11.72,;60.42,-10.38,;61.96,-10.38,;62.73,-9.05,;64.28,-9.05,;65.05,-10.39,;66.59,-10.39,;64.27,-11.72,;62.73,-11.72,;60.43,-13.06,;61.93,-13.39,;63.08,-12.37,;62.08,-14.92,;60.67,-15.54,;59.65,-14.39,;58.11,-14.39,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Dart Neuroscience LLC Curated by ChEMBL					Assay Description Inhibition of recombinant SGK1 (unknown origin) expressed in U2OS cells by cellular activity assay				ACS Med Chem Lett 6: 19-20 (2015) Article DOI: 10.1021/ml500480n BindingDB Entry DOI: 10.7270/Q2PZ5BFB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Sgk1 (Homo sapiens (Human))	BDBM50043020 (CHEMBL3355030) Show SMILES COc1ccc(F)c(c1)S(=O)(=O)Nc1ccc(cc1)-c1nc(O[C@H]2CC[C@H](O)CC2)c2c(C)n[nH]c2n1 |r,wU:23.24,wD:26.28,(46.54,-10.36,;45.77,-11.7,;46.55,-13.04,;45.79,-14.37,;46.56,-15.69,;48.1,-15.7,;48.87,-17.03,;48.87,-14.36,;48.1,-13.03,;50.41,-14.36,;51.74,-15.13,;50.41,-15.9,;51.18,-13.03,;52.72,-13.03,;53.49,-14.38,;55.03,-14.38,;55.81,-13.05,;55.03,-11.7,;53.49,-11.71,;57.34,-13.05,;58.11,-11.72,;59.65,-11.72,;60.42,-10.38,;61.96,-10.38,;62.73,-9.05,;64.28,-9.05,;65.05,-10.39,;66.59,-10.39,;64.27,-11.72,;62.73,-11.72,;60.43,-13.06,;61.93,-13.39,;63.08,-12.37,;62.08,-14.92,;60.67,-15.54,;59.65,-14.39,;58.11,-14.39,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<1.5	n/a	n/a	n/a	n/a	n/a	n/a
Dart Neuroscience LLC Curated by ChEMBL					Assay Description Inhibition of SGK1 (unknown origin) assessed as substrate phosphorylation				ACS Med Chem Lett 6: 19-20 (2015) Article DOI: 10.1021/ml500480n BindingDB Entry DOI: 10.7270/Q2PZ5BFB
					More data for this Ligand-Target Pair