BDBM50043346 1,8-Dihydroxy-10-(4-hydroxy-benzylidene)-10H-anthracen-9-one::1,8-dihydroxy-10-(4-hydroxybenzylidene)anthracen-9(10H)-one::CHEMBL131667

SMILES: [#8]-c1ccc(\[#6]=[#6]-2/c3cccc(-[#8])c3-[#6](=O)-c3c(-[#8])cccc-23)cc1

InChI Key: InChIKey=USTGZZZPDYRZIR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043346   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Bos taurus)	BDBM50043346 (1,8-Dihydroxy-10-(4-hydroxy-benzylidene)-10H-anthr...) Show SMILES [#8]-c1ccc(\[#6]=[#6]-2/c3cccc(-[#8])c3-[#6](=O)-c3c(-[#8])cccc-23)cc1 Show InChI InChI=1S/C21H14O4/c22-13-9-7-12(8-10-13)11-16-14-3-1-5-17(23)19(14)21(25)20-15(16)4-2-6-18(20)24/h1-11,22-24H	PDB MMDB Reactome pathway UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universität Regensburg Curated by ChEMBL					Assay Description Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomes				J Med Chem 36: 4099-107 (1994) BindingDB Entry DOI: 10.7270/Q2G44PC2
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Bos taurus)	BDBM50043346 (1,8-Dihydroxy-10-(4-hydroxy-benzylidene)-10H-anthr...) Show SMILES [#8]-c1ccc(\[#6]=[#6]-2/c3cccc(-[#8])c3-[#6](=O)-c3c(-[#8])cccc-23)cc1 Show InChI InChI=1S/C21H14O4/c22-13-9-7-12(8-10-13)11-16-14-3-1-5-17(23)19(14)21(25)20-15(16)4-2-6-18(20)24/h1-11,22-24H	PDB MMDB Reactome pathway UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universität Regensburg Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).				J Med Chem 36: 4099-107 (1994) BindingDB Entry DOI: 10.7270/Q2G44PC2
					More data for this Ligand-Target Pair