BDBM50043372 (E)-1,8-Dihydroxy-10-[3-(4-nitro-phenyl)-acryloyl]-10H-anthracen-9-one::CHEMBL130581

SMILES: Oc1cccc2C(C(=O)C=Cc3ccc(cc3)[N+]([O-])=O)c3cccc(O)c3C(=O)c12

InChI Key: InChIKey=VIGFACAVDTVYPO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50043372   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Bos taurus)	BDBM50043372 ((E)-1,8-Dihydroxy-10-[3-(4-nitro-phenyl)-acryloyl]...) Show SMILES Oc1cccc2C(C(=O)C=Cc3ccc(cc3)[N+]([O-])=O)c3cccc(O)c3C(=O)c12 |w:10.10| Show InChI InChI=1S/C23H15NO6/c25-17-5-1-3-15-20(16-4-2-6-18(26)22(16)23(28)21(15)17)19(27)12-9-13-7-10-14(11-8-13)24(29)30/h1-12,20,25-26H	PDB MMDB Reactome pathway UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universität Regensburg Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).				J Med Chem 36: 4099-107 (1994) BindingDB Entry DOI: 10.7270/Q2G44PC2
					More data for this Ligand-Target Pair