BDBM50043418 CHEMBL3355516
SMILES: O=S(=O)(Nc1ccccc1)c1ccc(cc1)-c1ncccc1Cc1ccccc1
InChI Key: InChIKey=DMUATXJZGOPROG-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
LIM domain kinase 2 (Homo sapiens (Human)) | BDBM50043418 (CHEMBL3355516) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese... | ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207 | |||||||||||
More data for this Ligand-Target Pair |