BDBM50043420 CHEMBL3355514

SMILES: O=c1ccnc(-c2ccc(cc2)S(=O)(=O)Nc2ccccc2)n1Cc1ccccc1

InChI Key: InChIKey=FJPRCIGXYORUGN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50043420   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043420 (CHEMBL3355514) Show SMILES O=c1ccnc(-c2ccc(cc2)S(=O)(=O)Nc2ccccc2)n1Cc1ccccc1 Show InChI InChI=1S/C23H19N3O3S/c27-22-15-16-24-23(26(22)17-18-7-3-1-4-8-18)19-11-13-21(14-12-19)30(28,29)25-20-9-5-2-6-10-20/h1-16,25H,17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair