BDBM50043615 CHEMBL3355498
SMILES: CN(Cc1ccc(cc1)C(O)CO)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1
InChI Key: InChIKey=LJBXWGVECYNLLM-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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LIM domain kinase 2 (Homo sapiens (Human)) | BDBM50043615 (CHEMBL3355498) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 92 | n/a | n/a | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese... | ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |