BDBM50043780 CHEMBL3356050

SMILES: COc1ccc(F)c(c1)S(=O)(=O)Nc1ccc(cc1)-c1cnc2c(N)n[nH]c2n1

InChI Key: InChIKey=UPNVOUINFODBLU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043780   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Sgk1 (Homo sapiens (Human))	BDBM50043780 (CHEMBL3356050) Show SMILES COc1ccc(F)c(c1)S(=O)(=O)Nc1ccc(cc1)-c1cnc2c(N)n[nH]c2n1 Show InChI InChI=1S/C18H15FN6O3S/c1-28-12-6-7-13(19)15(8-12)29(26,27)25-11-4-2-10(3-5-11)14-9-21-16-17(20)23-24-18(16)22-14/h2-9,25H,1H3,(H3,20,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi R&D Curated by ChEMBL					Assay Description Inhibition of human SGK1 using fluo-5(6)-carboxyfluorescein)-RPRAATF-NH2 fluorescently labeled peptide by substrate phosphorylation assay in presence...				ACS Med Chem Lett 6: 73-8 (2015) Article DOI: 10.1021/ml5003376 BindingDB Entry DOI: 10.7270/Q28S4RJT
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Sgk1 (Homo sapiens (Human))	BDBM50043780 (CHEMBL3356050) Show SMILES COc1ccc(F)c(c1)S(=O)(=O)Nc1ccc(cc1)-c1cnc2c(N)n[nH]c2n1 Show InChI InChI=1S/C18H15FN6O3S/c1-28-12-6-7-13(19)15(8-12)29(26,27)25-11-4-2-10(3-5-11)14-9-21-16-17(20)23-24-18(16)22-14/h2-9,25H,1H3,(H3,20,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi R&D Curated by ChEMBL					Assay Description Inhibition of human SGK1 using fluo-5(6)-carboxyfluorescein)-RPRAATF-NH2 fluorescently labeled peptide by substrate phosphorylation assay in presence...				ACS Med Chem Lett 6: 73-8 (2015) Article DOI: 10.1021/ml5003376 BindingDB Entry DOI: 10.7270/Q28S4RJT
					More data for this Ligand-Target Pair